Do you have to have a whirlpool bathtub or a walk-in closet? Will you be entertaining and thus in need of a dining table that can seat six or eight? Do you want benefits like priority dinner reservations and being first in line to get on or off the ship? Do you want to be pampered with extra-plush linens and bathrobes, fancy bath products and in-suite coffee and booze? You can find those amenities and more in most of the upper-level suites.
If you tend to get seasick, cabin location is really important. It is a question of engineering, really. The lower and more central you are in a ship, the less roll and sway you will feel. Even if you choose a balconied stateroom, choose the lowest level and the most midship one you can find. The higher decks and cabins at the very front (forward) or back (aft) of the ship will rock and roll the most.
Exception: Carnival has several cabins which are classified as inside cabins but actually have a french glass door which allows light into the room (no balcony, but the door can be opened). Carnival also has some cabins that have a window, but because the window has an obstructed view (that means there is a railing or object in the way) it is listed as an inside cabin. Royal Caribbean has some cabins that have a window but look out over an inside promenade area. These are called "promenade staterooms".
For many travelers, the decision on what size cabin to get is directly related to price. Who would not go for the huge suite if price were no obstacle? Yet it can be tricky to decide whether a balcony is worth the upgrade from a standard outside, or which suite to choose. Here are a few size-related considerations to take into account.