For some reason, most cruise lines assign their nicest and most expensive cabins to the highest decks, usually just below the pool deck (most likely because if you have a window or balcony, you have a more sweeping vista). Still, it is the pool deck that often causes the most noise problems, so if you do not want to hear scraping chairs at the crack of dawn or yee-hawing pool parties until the wee hours, go down a level. In fact, when it comes to noise, the best bet is to select a cabin that is both above and below other cabins.
Inside cabins with no views at all are typically the smallest, cheapest cabins onboard. They are great options for budget-minded travelers who do not intend to spend a lot of time in their stateroom, or who want to sleep all day in absolute pitch dark. They are less ideal for cruisers prone to seasickness, those who need natural light and groups who require a lot of in-cabin space. Not everyone will be happy in an inside cabin; it is worth upgrading if the lack of light will put a damper on your vacation.
Exception: Royal Caribbean and other cruise lines will also use sub categories to distinquish between how many occupants the cabin will sleep. Therefore a cabin that can sleep up to 4 people will be a different sub category from a cabin that sleeps only 2 people.
Do you have to have a whirlpool bathtub or a walk-in closet? Will you be entertaining and thus in need of a dining table that can seat six or eight? Do you want benefits like priority dinner reservations and being first in line to get on or off the ship? Do you want to be pampered with extra-plush linens and bathrobes, fancy bath products and in-suite coffee and booze? You can find those amenities and more in most of the upper-level suites.
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